CAIMP - CAS 1507367-51-2

CAIMP acts as a STING agonist and has been shown to more effectively activate STING-dependent IRF and NF-κB signaling pathways in mammalian cells in vitro when compared to standard murine (DMXAA) and human (2',3'-cGAMP) STING agonists. In ex vivo experiments with human blood, cAIMP analogs can induce the production of type I interferons (IFNs) and pro-inflammatory cytokines.

NF-κB, IFNAR

Immunology/Inflammation, NF-κB

1507314

C20H23N9O13P2

659.4

O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@]4([C@]1(OP(=O)(O)OC[C@@]5([C@@](OP(=O)(O)OC4)([C@@H](O)[C@@H](O5)N6C7=C(N=C6)C(=O)N=CN7)[H])[H])[H])[H]

-20°C

Ice Packs

Small Compound