Calcimycin - CAS 52665-69-7

Calcimycin (A-23187) is an ionophorous, polyether carboxylic antibiotic from Streptomyces chartreusensis. It binds and transports calcium and other divalent cations across membranes, uncouples oxidative phosphorylation, and inhibits ATPase of rat liver mitochondria. The substance is primarily used as a biochemical tool to study the role of divalent cations in various biological systems.

OXPHOS, Apoptosis, Antifungal, Autophagy, Antibacterial, Antibiotic

Autophagy, Apoptosis, Microbiology/Virology

52589

0.98

C29H37N3O6

523.62

CNc1ccc2oc(C[C@H]3OC4(CC[C@H]3C)O[C@H]([C@H](C)C(=O)c3ccc[nH]3)[C@H](C)C[C@H]4C)nc2c1C(O)=O

-20°C

Ice Packs

Natural Product