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Calmidazolium chloride - CAS 57265-65-3

Calmidazolium chloride - CAS 57265-65-3

SKU:MF-0004814-01

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  • Bioactivity

    Calmidazolium chloride (R 24571) is a calmodulin (CaMK) antagonist with a Kd of 3 nM, which inhibits CaM-dependent phosphodiesterase (IC50 = 0.15 μM) and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase (IC50 = 0.35 μM) . It also induces apoptosis in certain cancer cell lines.

  • Target

    CaMK, Autophagy

  • Related Pathways

    Neuroscience, Autophagy

  • CAS Number

    57197

  • Purity

    0.9853

  • Molecular Formula

    C31H23Cl7N2O

  • Molecular Weight

    687.7

  • SMILES

    [Cl-].Clc1ccc(cc1)C(c1ccc(Cl)cc1)[n+]1ccn(CC(OCc2ccc(Cl)cc2Cl)c2ccc(Cl)cc2Cl)c1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound