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CALR ligand 1 - CAS 3055854-78-6

CALR ligand 1 - CAS 3055854-78-6

MF-0118387-01

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Product Details

  • Bioactivity

    CALR ligand 1 (Compound 2a) is a calreticulin (CALR) ligand with anti-tumor activity against triple-negative breast cancer (TNBC) cells, exhibiting an IC50 of 0.1 μM. It induces intracellular calcium overload, leading to apoptosis in TNBC cells, making it a promising candidate for further research on triple-negative breast cancer.

  • Target

    Apoptosis

  • Related Pathways

    Apoptosis

  • CAS Number

    3055770

  • Molecular Formula

    C17H17ClN4O3S

  • Molecular Weight

    392.86

  • SMILES

    O=C(NC1=NNC2=NC=C(C=C21)C=3C=CC(=CC3)S(=O)(=O)C(C)C)CCl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound