CAM 833 - CAS 2758364-02-0

CAM 833 is an effective orthosteric inhibitor of the BRCA2-RAD51 interaction, inhibiting RAD51 aggregation, enhancing DNA damage-induced apoptosis, increasing 4N cell cycle arrest, and disrupting homologous DNA repair (HDR), and can be used for cancer therapy.

DNA/RNA Synthesis, Cell Cycle Arrest, Apoptosis

Cell Cycle/Checkpoint, Apoptosis, DNA Damage/DNA Repair

2758364-02-0

0.9983

C26H26ClFN4O5

528.96

C(N[C@@H](C)C1=C(Cl)C=C(OC)C=C1)(=O)[C@H]2N(C(CNC(=O)C3=NC4=C(C=C3)C=C(F)C=C4)=O)C[C@H](O)C2

-20°C

Ice Packs

Small Compound