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Molfinity

CAN508 - CAS 140651-18-9

CAN508 - CAS 140651-18-9

MF-0093846-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    CAN508 is a potent ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It also competitively inhibits Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 μM and 20 μM, respectively. CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. [Antitumor activity.]

  • Target

    CDK

  • Related Pathways

    Cell Cycle/Checkpoint

  • CAS Number

    140624

  • Purity

    >99.99%

  • Molecular Formula

    C9H10N6O

  • Molecular Weight

    218.22

  • SMILES

    Nc1n[nH]c(N)c1\N=N\c1ccc(O)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound