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Canagliflozin - CAS 842133-18-0

Canagliflozin - CAS 842133-18-0

SKU:MF-0019349-01

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  • Bioactivity

    Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor that inhibits CHO cells expressing mSGLT2, rSGLT2, and hSGLT2 (IC50=2/3.7/4.4 nM) . Canagliflozin can be used for the treatment of type II diabetes mellitus (T2DM) .

  • Target

    SGLT

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    842115

  • Purity

    >99.99%

  • Molecular Formula

    C24H25FO5S

  • Molecular Weight

    444.52

  • SMILES

    O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O)C2=CC(CC=3SC(=CC3)C4=CC=C(F)C=C4)=C(C)C=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound