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Canakinumab - CAS 914613-48-2
Canakinumab - CAS 914613-48-2
SKU:MF-0098730-01
Regular price
$207.07 USD
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$207.07 USD
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Product Details
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Bioactivity
Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody that inhibits human and chorioallantoic monkey IL-1β with IC50 values of 43.6 and 40.8 pM, respectively. It exhibits anti-inflammatory activity by neutralizing IL-1β signaling, and it has been used for the treatment of gout and coronary artery disease.
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Target
IL Receptor, Interleukin
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Related Pathways
Immunology/Inflammation
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CAS Number
914563
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Purity
0.988
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Inhibitory Antibodies