Candesartan Cilexetil - CAS 145040-37-5

Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM) . Upon hydrolysis to candesartan during gastrointestinal absorption, it selectively competes with angiotensin II for binding to the angiotensin II receptor subtype 1 (AT1) in vascular smooth muscle, blocking angiotensin II-mediated vasoconstriction and inducing vasodilatation.

RAAS, Apoptosis

Apoptosis, Endocrinology/Hormones

144998

>99.99%

C33H34N6O6

610.66

C(N1C=2C(N=C1OCC)=CC=CC2C(OC(OC(OC3CCCCC3)=O)C)=O)C4=CC=C(C=C4)C5=C(C=CC=C5)C=6NN=NN6

-20°C

Ice Packs

Small Compound