Canfosfamide hydrochloride - CAS 439943-59-6

Canfosfamide Hydrochloride is the hydrochloride salt of a modified glutathione analogue with potential antineoplastic activity. Canfosfamide is selectively activated by glutathione S-transferase P1-1 into an alkylating metabolite that forms covalent linkages with nucleophilic centers in tumor cell DNA, which may induce a cellular stress response and cytotoxicity, and decrease tumor proliferation.

DNA Alkylator/Crosslinker, Others

DNA Damage/DNA Repair, Others

439878

C26H41Cl5N5O10PS

823.93

P(N(CCCl)CCCl)(N(CCCl)CCCl)(OCCS(C[C@@H](C(N[C@@H](C(O)=O)C1=CC=CC=C1)=O)NC(CC[C@@H](C(O)=O)N)=O)(=O)=O)=O.Cl

-20°C

Ice Packs

Small Compound