Cantharidic acid - CAS 28874-45-5

Cantharidic acid is a selective inhibitor of protein phosphatase 2 (PP2A) and protein phosphatase 1 (PP1) . It impedes cell viability by upregulating the ERK1/2, p38, and JNK1/2 pathways, causes cell cycle arrest at the sub-G1 phase, and induces apoptosis in NPC-39 and HONE-1 cells.

Phosphatase, Apoptosis, p38 MAPK, JNK, ERK

Apoptosis, MAPK, Metabolism

28824

C10H14O5

214.22

C(O)(=O)[C@@]1(C)[C@](C(O)=O)(C)[C@]2(O[C@@]1(CC2)[H])[H]

-20°C

Ice Packs

Small Compound