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Capivasertib - CAS 1143532-39-1

Capivasertib - CAS 1143532-39-1

SKU:MF-0013932-01

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  • Bioactivity

    Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity. Capivasertib has antitumor activity for the treatment of breast cancer.

  • Target

    PKA, Akt, mTOR, Autophagy

  • Related Pathways

    Autophagy, Tyrosine Kinase/Adaptors, PI3K/Akt/mTOR signaling, Cytoskeletal Signaling

  • CAS Number

    1143492

  • Purity

    0.996

  • Molecular Formula

    C21H25ClN6O2

  • Molecular Weight

    428.92

  • SMILES

    NC1(CCN(CC1)c1ncnc2[nH]ccc12)C(=O)N[C@@H](CCO)c1ccc(Cl)cc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound