Capmatinib xHCl - CAS 1029714-89-3

Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activity in cells (IC50 values range from 0.3 to 1.1 nM) .

Apoptosis, c-Met/HGFR

Tyrosine Kinase/Adaptors, Apoptosis

1029622

0.9981

C23H18ClFN6O

448.89

Cl.CNC(=O)c1ccc(cc1F)-c1cnc2ncc(Cc3ccc4ncccc4c3)n2n1

-20°C

Ice Packs

Small Compound