Carbonic anhydrase inhibitor 14 - CAS 2410402-75-2

Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibits CDK2 with an IC 50 of 20.3 μM and demonstrates significant antitumor activity [1].

CDK, Others, Carbonic Anhydrase

Metabolism, Others, Cell Cycle/Checkpoint

2410325

C18H17N7O2S

395.44

N(=N/C1=CC=C(S(N)(=O)=O)C=C1)\C2=C3N(C=C(N3)C4=CC=C(C)C=C4)N=C2N

-20°C

Ice Packs

Small Compound