C[Arg-Arg-Arg-Arg-Nal-Nal-Nal] - CAS 2619854-01-0

Compound 9C [c[Arg-Arg-Arg-Arg-Nal-Nal-Nal]] demonstrates broad-spectrum efficacy against drug-resistant Gram-positive and Gram-negative bacteria. It exhibits minimum inhibitory concentrations (MICs) of 3.1 μg/mL for MRSA (ATCC BAA-1556), 3.1 μg/mL for S. aureus (ATCC 29213), 12.5 μg/mL for P. aeruginosa (ATCC 27883), and 25 μg/mL for E. coli (ATCC 25922) [1].

Antibacterial

Microbiology/Virology

2619854-01-0

C63H81N19O7

1216.44

C(C1=CC2=C(C=C1)C=CC=C2)[C@H]3C(=O)N[C@@H](CC4=CC5=C(C=C4)C=CC=C5)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](CC6=CC7=C(C=C6)C=CC=C7)C(=O)N3

-20°C

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Peptide