Casein kinase 1δ-IN-27 - CAS 1095706-65-2

Casein kinase1δ-IN-27 (Compound 8) is an inhibitor of casein kinase 1 (CK1), effectively inhibiting CK1α, CK1δ, CK1ε, and p38α with IC50 values of 22, 16.5, 9.41, and 14.8 nM, respectively. It also suppresses DUX4 expression, with an IC50 of 10 nM.

Casein Kinase, p38 MAPK

Stem Cells, Metabolism, MAPK

1095639

C21H19FN6

374.414

FC1=CC=C(C=C1)C=2N=C3C=CC(=NN3C2C=4C=CN=CC4)N5CCNCC5

-20°C

Ice Packs

Small Compound