Casein kinase 1δ-IN-29 - CAS 1177418-39-1

Casein kinase1δ-IN-29 (Compound 18) is an inhibitor that targets p38α and casein kinase 1 (CK1), exhibiting inhibitory effects on p38α, CK1δ, and CK1ε with IC50 values of 0.041 μM, 0.005 μM, and 0.447 μM, respectively. This compound causes cell cycle arrest at the subG1 phase and induces apoptosis in AC1-M88 cells.

Apoptosis, Casein Kinase, p38 MAPK

Apoptosis, Metabolism, Stem Cells, MAPK

1177378

C26H23FN4O4S

506.549

S(C)(=O)C=1NC(=C(N1)C2=CC=C(F)C=C2)C=3C=C(NC(/C=C/C4=C(OC)C=C(OC)C=C4)=O)N=CC3

-20°C

Ice Packs

Small Compound