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Casein Kinase inhibitor A86 - CAS 2079069-01-3

Casein Kinase inhibitor A86 - CAS 2079069-01-3

SKU:MF-0046711

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  • Bioactivity

    Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α) and also inhibits CDK7 (TFIIH) and CDK9 (P-TEFb) . It induces apoptosis in leukemia cells, exhibiting substantial anti-leukemic effects.

  • Target

    Others, Casein Kinase, Apoptosis, CDK

  • Related Pathways

    Stem Cells, Cell Cycle/Checkpoint, Metabolism, Others, Apoptosis

  • CAS Number

    2079069-01-3

  • Molecular Formula

    C18H25FN6

  • Molecular Weight

    344.438

  • SMILES

    Cn1ncc(c1CC1CC1)-c1nc(N[C@H]2CC[C@H](N)CC2)ncc1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound