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Casein Kinase inhibitor A86 - CAS 2079069-01-3
Casein Kinase inhibitor A86 - CAS 2079069-01-3
SKU:MF-0046711
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Product Details
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Bioactivity
Casein Kinase inhibitor A86 is a highly effective and orally bioavailable inhibitor of casein kinase 1α (CK1α) and also inhibits CDK7 (TFIIH) and CDK9 (P-TEFb) . It induces apoptosis in leukemia cells, exhibiting substantial anti-leukemic effects.
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Target
Others, Casein Kinase, Apoptosis, CDK
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Related Pathways
Stem Cells, Cell Cycle/Checkpoint, Metabolism, Others, Apoptosis
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CAS Number
2079069-01-3
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Molecular Formula
C18H25FN6
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Molecular Weight
344.438
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SMILES
Cn1ncc(c1CC1CC1)-c1nc(N[C@H]2CC[C@H](N)CC2)ncc1F
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound