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β-catenin-IN-37 - CAS 1783856-40-5
β-catenin-IN-37 - CAS 1783856-40-5
SKU:MF-0036132
Regular price
$901.17 USD
Regular price
$630.50 USD
Sale price
$901.17 USD
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Product Details
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Bioactivity
β-Catenin-IN-37 is a selective inhibitor of the protein-protein interaction between β-Catenin and T-cell factor (Tcf), known as β-catenin/Tcf PPI. It effectively inhibits canonical Wnt signaling and impedes the growth of colorectal cancer cells SW480 and HCT116, with IC50 values of 20 μM and 31 μM, respectively.
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Target
Others, Wnt/beta-catenin
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Related Pathways
Cytoskeletal Signaling, Others, Stem Cells
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CAS Number
1783856-40-5
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Molecular Formula
C13H9N9O
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Molecular Weight
307.277
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SMILES
C(Cn1c2ccccc2c2nc3nonc3nc12)c1nnn[nH]1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound