Caulophyllogenin - CAS 52936-64-8

Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae) . Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the prevention and treatment of inflammatory diseases, type-2 diabetes, obesity and metabolic syndrome.

PPAR, IL Receptor, Immunology/Inflammation related, TNF

Metabolism, Apoptosis, DNA Damage/DNA Repair, Immunology/Inflammation

52864

0.9969

C30H48O5

488.7

C(O)(=O)[C@]12[C@](C=3[C@@](C)(C[C@H]1O)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)([C@@](CO)(C)[C@@H](O)CC5)[H])[H])(CC(C)(C)CC2)[H]

-20°C

Ice Packs

Natural Product