Cavα2δ1&NET-IN-3 - CAS 2143584-82-9

Cavα2δ1&NET-IN-3 (example 216) is an inhibitor targeting both the α2δ subunit of voltage-gated calcium channels (VGCC) and the noradrenaline transporter (NET), exhibiting inhibitory constants (Ki) ranging from 100 to 500 nM for the human α2δ-1 subunit of the Cav2.2 calcium channel and NET, respectively.

Others, Calcium Channel

Membrane transporter/Ion channel, Metabolism, Others

2143493

C24H30N6O2S

466.6

O=C1C=2C(=NC(NCC)=NC2)N(C)CCN1C3=CC(O[C@@H](CCNC)C4=CC=CS4)=CC=C3

-20°C

Ice Packs

Small Compound