Cav 3.1 blocker 1 - CAS 2158201-04-6

Cav 3.1 blocker 1 (compound 12) is a T-type calcium channel inhibitor with an IC50 value of 160 nM for Cav3.1. It exhibits weaker inhibition on Cav 3.2 with an IC50 of 5000 nM and shows no inhibitory effect on Cav 3.3 and Cav 1.2 (IC50 > 10000 nM) .

Calcium Channel

Metabolism, Membrane transporter/Ion channel

2158201-04-6

C26H19F6N3O2

519.438

O=C(NCC=1C=CC=CC1OCC(F)(F)F)C2=NN(C3=CC=C(F)C=C3)C(C=4C=CC=CC4)=C2C(F)F

-20°C

Ice Packs

Small Compound