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Molfinity

CAY10602 - CAS 374922-43-7

CAY10602 - CAS 374922-43-7

MF-0018764-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    CAY10602 is a SIRT1 activator derived from high throughput screening for compounds that enhance SIRT1-mediated deacetylation of a SIRT1-specific substrate. Functional assays indicate that CAY10602 dose-dependently suppresses NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells, achieving approximately 75% inhibition at 60 μM without cytotoxicity.

  • Target

    Sirtuin

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    374872

  • Purity

    >99.99%

  • Molecular Formula

    C22H15FN4O2S

  • Molecular Weight

    418.44

  • SMILES

    Nc1c(c2nc3ccccc3nc2n1-c1ccc(F)cc1)S(=O)(=O)c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound