CAY10704 - CAS 101784-44-5

CAY10704 is a potent inhibitor of hepatitis C virus (HCV) infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 μM) . It displays good pharmacokinetics in mice when delivered intraperitoneally, with preferential liver distribution without significant hepatotoxicity. CAY10704 is selective for HCV over dengue virus (EC50 = 4.62 μM) .

Others, HCV Protease

Microbiology/Virology, Proteases/Proteasome, Others

101735

C18H20Cl2N2

335.27

C(C1=CC=C(Cl)C=C1)(C2=CC=C(Cl)C=C2)N3CCN(C)CC3

-20°C

Ice Packs

Small Compound