CAY10742 - CAS 1649473-91-5

CAY10742 is an orally bioavailable oxadiazole antibiotic.1It is active against the Gram-positive bacteriaS. aureus, S. epidermidis, S. haemolyticus, B. cereus, B. licheniformis, E. faecalis, andE. faecium (MICs = 1-4 μg/ml), including laboratory strains and clinical isolates with varying degrees of resistance to methicillin, vancomycin, linezolid, and other antibiotics. CAY10742 (40 mg/kg) reduces the number of bacteria in mouse neutropenic thigh models of linezolid-sensitive or -resistant methicillin-resistantS. aureus (MRSA) infection.

Others, Antibacterial

Microbiology/Virology, Others

1649473-91-5

C22H14FN3O2

371.371

Fc1ccc(Oc2ccc(cc2)-c2noc(n2)-c2ccc3[nH]ccc3c2)cc1

-20°C

Ice Packs

Small Compound