CAY10770 - CAS 2428734-45-4

CAY10770 is an inhibitor of the cytochrome P450 (CYP) isoform CYP4Z1 (IC50= 5.9 μM) .1It is selective for CYP4Z1 over CYP4A11, CYP4F2, CYP4F3a, CYP4F3b (IC50s = 187-282 μM) but does inhibit CYP4F8 and CYP4F12 (IC50s = 167 and 91 μM, respectively) . CAY10770 (3 μM) inhibits the production of 14 (15) -EET, 19-HETE, and 14 (15) -DiHET by 83, 86, and 80%, respectively, in T47D breast cancer cells expressing CYP4Z1.

Cytochromes P450, Others

Metabolism, Others

2428685

C14H20N4O2

276.33

N(CCCCCCCC(O)=O)N1C=2C(N=N1)=CC=CC2

-20°C

Ice Packs

Small Compound