CB-0821 - CAS 81430-62-8

CB-0821 is a high-affinity CCR5 inhibitor with a Ki of 0.04 nM. It effectively binds to the hydrophobic pocket of the CCR5 protein, hindering the interaction between viral proteins and CCR5, thereby blocking virus entry. CB-0821 holds potential for anti-HIV research.

HIV Protease, CCR

GPCR/G Protein, Proteases/Proteasome, Immunology/Inflammation, Microbiology/Virology

81360

C35H24N8

556.62

N1=C2N=C(C=C(C=3C=CC=CC3)N2N=C1CC=4N=C5N=C(C=C(C=6C=CC=CC6)N5N4)C=7C=CC=CC7)C=8C=CC=CC8

-20°C

Ice Packs

Small Compound