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CB-184 - CAS 165307-47-1
CB-184 - CAS 165307-47-1
SKU:MF-0110806-01
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Product Details
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Bioactivity
CB-184 is a selective ligand for sigma-2 (σ2) receptors, with Ki values of 7436 nM for sigma-1 (σ1) and 13.4 nM for sigma-2 (σ2), and it promotes apoptosis with antitumor activity.
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Target
Apoptosis, Sigma receptor
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Related Pathways
GPCR/G Protein, Apoptosis
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CAS Number
165259
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Molecular Formula
C22H21Cl2NO2
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Molecular Weight
402.31
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SMILES
O=C\1C[C@@]2(C[C@](/C1=C\C3=CC(Cl)=C(Cl)C=C3)(N(C)CC2)[H])C4=CC(O)=CC=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound