CB039 - CAS 3056259-55-0

CB039 is a selective degrader targeting RBM39 (RNA binding motif protein 39) . It facilitates the formation of a ternary complex between RBM39 and the E3 ubiquitin ligase CUL4-DCAF15, resulting in the proteasomal degradation of RBM39. CB039 holds promise for research into cancers dependent on RBM39, such as acute myeloid leukemia (AML) and ovarian cancer.

Molecular Glues

PROTAC

3056204

C23H23N5O5S

481.524

N(S(=O)(=O)C1=CC(NC(C(=O)N2[C@@H](CO)CCC2)=O)=CC=C1)C3=C4C(C(C#N)=CN4)=C(C)C=C3

-20°C

Ice Packs

PROTAC