CB10-277 - CAS 7203-91-0

CB10-277 is a synthetic derivative of dimethylphenyl-triazene related to dacarbazine, with antineoplastic properties. Related to the agent dacarbazine, CB10-277 is converted in vivo to a monomethyl triazene form that alkylates DNA, resulting in inhibition of DNA replication and repair; in addition, this agent may act as a purine analogue, resulting in inhibition of DNA synthesis, and may interact with protein sulfhydryl groups.

Others, DNA Alkylator/Crosslinker, Nucleoside Antimetabolite/Analog

Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint

7112

C9H11N3O2

193.2

CN(C)\N=N\C1=CC=C(C=C1)C(O)=O

-20°C

Ice Packs

Small Compound