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CB2 receptor agonist 9 - CAS 2374894-21-8
CB2 receptor agonist 9 - CAS 2374894-21-8
SKU:MF-0112447-01
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Product Details
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Bioactivity
CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-α, IL-1β, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.
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Target
Cannabinoid Receptor
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Related Pathways
GPCR/G Protein
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CAS Number
2374865
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Molecular Formula
C16H23N3O2S
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Molecular Weight
321.44
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SMILES
O=C(NC(C)(C)CO)C1=NN(C(=C1)C=2SC=CC2)CCCC
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound