CBL 0100 free base - CAS 1197996-83-0

CBL 0100 free base is an HIV-1 transcription inhibitor that blocks HIV-1 replication and reactivation in vitro and in ex vivo models. It targets the chromatin-associated transcription (FACT) complex, reducing the occupancy of RNA Polymerase II and FACT in the HIV-1 promoter region, and can be used as a latency-reversing agent (LRA) in cART therapy.

HIV Protease, Others, DNA/RNA Synthesis

Others, Proteases/Proteasome, Cell Cycle/Checkpoint, Microbiology/Virology, DNA Damage/DNA Repair

1197913

0.9886

C24H26N2O2

374.48

O=C1C2=CC=C3C(C=4C(=CC=C5C(=O)CCC54)N3CCN(CC)CC)=C2CC1

-20°C

Ice Packs

Small Compound