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Cbl-b-IN-11 - CAS 2815225-15-9
Cbl-b-IN-11 - CAS 2815225-15-9
SKU:MF-0157529-01
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Product Details
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Bioactivity
Cbl-b-IN-11 (Compound 466) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half-maximal inhibitory concentrations (IC50s) of 6.4 nM and 6.1 nM, respectively [1].
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Target
E1/E2/E3 Enzyme
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Related Pathways
Ubiquitination
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CAS Number
2815201
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Molecular Formula
C31H35F5N6O
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Molecular Weight
602.64
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SMILES
C(C1(CC(F)(F)C1)C2=CC(=CC(NCC)=C2)N3CC=4C(C3=O)=CC(CNC5(C)CCC5)=CC4C(F)(F)F)C=6N(C)C=NN6
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound