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Cbl-b-IN-2 - CAS 2503325-21-9

Cbl-b-IN-2 - CAS 2503325-21-9

SKU:MF-0052332-01

Regular price $1,927.85 USD
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  • Bioactivity

    Cbl-b-IN-2 is an orally active biological compound that inhibits the E3 enzyme Casitas b lineage lymphoma proto-oncogene b (Cbl-b) in the ubiquitin proteasome pathway and can be used in the study of diseases that modulate the immune system and are susceptible to regulation by the immune system. Cbl-b-IN-2 can also be used in cancer research alone or in combination with one or more immune checkpoint inhibitors, antitumour agents and radiopharmaceuticals.

  • Target

    Others, E3 Ligase Ligand-Linker Conjugate

  • Related Pathways

    PROTAC, Others

  • CAS Number

    2503295

  • Molecular Formula

    C29H30F5N5O2

  • Molecular Weight

    575.57

  • SMILES

    C(C1(COC1)C2=CC(=CC=C2)N3CC=4C(C3=O)=CC(CN5C[C@@H](C)C(F)(F)CC5)=CC4C(F)(F)F)C=6N(C)C=NN6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC