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Cbl-b-IN-8 - CAS 2815223-33-5

Cbl-b-IN-8 - CAS 2815223-33-5

MF-0157526-01

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Product Details

  • Bioactivity

    Cbl-b-IN-8 (Compound 293) is an inhibitor of casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl, with half maximal inhibitory concentrations (IC50s) of 5.5 nM and 7.8 nM, respectively [1].

  • Target

    E1/E2/E3 Enzyme

  • Related Pathways

    Ubiquitination

  • CAS Number

    2815185

  • Molecular Formula

    C35H44F3N7O3

  • Molecular Weight

    667.76

  • SMILES

    C(C1(COC1)C=2C=C(N=C(OC3CCCC3)C2)N4CC=5C(C4=O)=CC(CN6[C@@H]([C@H](C)C)CN(C)CC6)=CC5C(F)(F)F)C=7N(C)C=NN7

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound