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Molfinity

CBR-470-1 - CAS 2416095-06-0

CBR-470-1 - CAS 2416095-06-0

MF-0050516

$36.16 USD
$36.16 USD
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Product Details

  • Bioactivity

    CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protects SH-SY5Y neuronal cells from MPP+-induced cytotoxicity by activating the Keap1-Nrf2 cascade. cytotoxicity induced by MPP+.

  • Target

    PGK1, Nrf2

  • Related Pathways

    Immunology/Inflammation, Metabolism

  • CAS Number

    2416095-06-0

  • Purity

    0.9887

  • Molecular Formula

    C14H20ClNO4S2

  • Molecular Weight

    365.9

  • SMILES

    S(=O)(=O)([C@@H]1[C@@H](NCC(C)C)CS(=O)(=O)C1)C2=CC=C(Cl)C=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound