CC-90005 - CAS 1799574-70-1

CC-90005 is a potent, selective, and orally active inhibitor of protein kinase C-θ (PKC-θ) with an IC50 of 8 nM, demonstrating strong selectivity over PKC-δ (IC50=4440 nM) . Additionally, CC-90005 can inhibit T cell activation by IL-2 expression[1].

Others, PKC

Chromatin/Epigenetic, Others, Cytoskeletal Signaling

1799503

C21H27F2N7O2

447.48

CC(F)(F)COc1ncncc1CNc1ncc(C#N)c(N[C@@H]2CC[C@H](O)C(C)(C)C2)n1

-20°C

Ice Packs

Small Compound