CC4 - CAS 492-02-4

High affinity and subtype selective α6β2 and α4β2 partial agonist (Ki values are 12 and 26nM for rat α6β2 and α4β2 receptors respectively) . Has low affinity for α3β4 and α7 receptors (Ki values are 4.8 and 13 μM for human α3β4 and rat α7 receptors respectively) . Stimulates dopamine release from striatal slices in vitro. Attenuates nicotine-induced self-administration and conditional place preference in rats.

Others, AChR

Neuroscience, Others

492-02-4

C24H30N4O2

406.52

O=c1cccc2C3C[C@@H](CN(CCN4C[C@@H]5CC(C4)c4cccc(=O)n4C5)C3)Cn12

-20°C

Ice Packs

Small Compound