CCR4 antagonist 3 hydrochloride - CAS 2174938-71-5

CCR4 antagonist 3 hydrochloride is an orally active, potent and selective CCR4 antagonist. CCR4 antagonist 3, featuring a novel piperidinyl-azetidine motif, has IC 50 s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4 antagonist 3 has antitumor activity.

Others, CCR

Immunology/Inflammation, GPCR/G Protein, Others, Microbiology/Virology

2174862

C24H27Cl2N7O.xHCl

[C@H](C)(N1C=2C(C(C#N)=N1)=NC=C(N2)N3CC(C3)[C@@H]4CN(CCO)CCC4)C5=C(Cl)C=C(Cl)C=C5.Cl

-20°C

Ice Packs

Small Compound