CCR6 inhibitor 1 - CAS 2437547-04-9

CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively) . CCR6 is associated with both autoimmune and non-autoimmune diseases, so CCR6 inhibitor 1 is useful for in vitro and in vivo pathophysiology studies as a small molecule inhibitor of CCR6.

CCR

GPCR/G Protein, Immunology/Inflammation, Microbiology/Virology

2437547-04-9

0.9989

C24H23F3N4O3S

504.52

NC(=O)c1cc(ccn1)-c1ccc(cc1)S(=O)(=O)[C@H]1CC[C@@H](CC1)Nc1ccc(cn1)C(F)(F)F

-20°C

Ice Packs

Small Compound