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CCT018159 - CAS 171009-07-7
CCT018159 - CAS 171009-07-7
SKU:MF-0097109-01
Regular price
$33.17 USD
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$33.17 USD
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Product Details
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Bioactivity
CCT018159 is a 3,4-diarylpyrazole resorcinol, an ATP-competitive HSP90ATPase inhibitor that inhibits human Hsp90β and yeast Hsp90 with IC50s of 3.2 and 6.6 μM, respectively.CCT018159 inhibits key endothelial and tumor cell functions associated with invasion and angiogenesis. CCT018159 caused cellular inhibition associated with G1 phase block and induced apoptosis.
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Target
Apoptosis, HSP
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Related Pathways
Metabolism, Apoptosis, Cytoskeletal Signaling
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CAS Number
171009-07-7
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Purity
0.9979
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Molecular Formula
C20H20N2O4
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Molecular Weight
352.38
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SMILES
CC1=C(C(=NN1)C2=CC(CC)=C(O)C=C2O)C=3C=C4C(=CC3)OCCO4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound