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Molfinity
CCT070535 - CAS 485319-41-3
CCT070535 - CAS 485319-41-3
SKU:MF-0142492-01
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Product Details
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Bioactivity
CCT070535 inhibits TCF-dependent transcription at the TCF level, displaying GI50 values of 17.6 μM in HT29 (APC mutation), 11.1 μM in HCT116 (oncogenic β-catenin), 11.8 μM in SW480 (APC mutation), and 13.4 μM in SNU475 (Axin mutation) cells.
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Target
Wnt/beta-catenin
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Related Pathways
Cytoskeletal Signaling, Stem Cells
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CAS Number
485275
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Molecular Formula
C20H13Cl2N3O2
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Molecular Weight
398.24
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SMILES
O=C1C(=C([O-])[N+]=2N=C(Cl)C=CC2N1C3=CC=C(Cl)C=C3)CC=4C=CC=CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound