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CCT241161 - CAS 1163719-91-2
CCT241161 - CAS 1163719-91-2
SKU:MF-0095578-01
Regular price
$137.94 USD
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$137.94 USD
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Product Details
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Bioactivity
CCT241161 is an orally active pan-RAF inhibitor, with IC50 values of 3, 6, 10, 15, and 30 nM for LCK, CRAF, SRC, V600E-BRAF, and BRAF, respectively. It exhibits significant activity against BRAF and NRAS mutant melanomas and demonstrates anticancer cell proliferative effects [1].
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Target
Raf, Apoptosis, Src
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Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors, Apoptosis, MAPK
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CAS Number
1163626
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Purity
>99.99%
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Molecular Formula
C28H27N7O3S
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Molecular Weight
541.62
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SMILES
N(C(NC1=C(SC)C=C(OC2=C3C(=NC=C2)NC(=O)C=N3)C=C1)=O)C=4N(N=C(C(C)(C)C)C4)C5=CC=CC=C5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound