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Molfinity

CCW16 - CAS 2361138-33-0

CCW16 - CAS 2361138-33-0

MF-0047481-01

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Product Details

  • Bioactivity

    CCW16 is a covalent E3 ubiquitin ligase RNF4 ligand exhibiting cysteine reactivity, capable of inducing ferroptosis in AML cells by activating ROS signalling. CCW16 may be utilised in synthesising PROTAC degraders such as CCW 28-3.

  • Target

    ROS, Ligand for E3 Ligase, Ferroptosis

  • Related Pathways

    Apoptosis, PROTAC, Immunology/Inflammation

  • CAS Number

    2361105

  • Purity

    0.97

  • Molecular Formula

    C22H20ClNO3

  • Molecular Weight

    381.85

  • SMILES

    O=C(N(C1=CC=C(OC2=CC=C(OC)C=C2)C=C1)CC=3C=CC=CC3)CCl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound