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CD38 inhibitor 3 - CAS 2857868-82-5

CD38 inhibitor 3 - CAS 2857868-82-5

SKU:MF-0147176-01

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  • Bioactivity

    CD38 Inhibitor 3 (compound 1), with an IC50 of 11 nM, is a potent agent that enhances mitochondrial biogenesis, diminishes lactate levels, and augments both NAD+ content and Nrf2 expression. In a Pus1 -/- mouse model of mitochondrial myopathy, it also elevates muscle function and bolstering exercise capacity [1].

  • Target

    CD38

  • Related Pathways

    Immunology/Inflammation

  • CAS Number

    2857781

  • Molecular Formula

    C16H14F3N7O3

  • Molecular Weight

    409.32

  • SMILES

    C(NC=1C=NC(OCCOC)=NC1)(=O)C2=NC(=NC(C(F)(F)F)=C2)N3C=CN=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound