CDD-1431 - CAS 3034216-31-1

CDD-1431 is a highly selective BMPR2 kinase inhibitor with a Kiapp of 20.6 nM. It inhibits BRE reporter gene activity, exhibiting an IC50 of 4.87 μM. BMPs regulate cellular processes across various tissue types such as the kidneys, skeletal muscle, heart, and reproductive organs, and can induce ectopic bone formation.

TGF-beta/Smad

Stem Cells

3034184

C33H38N8O5S

658.77

O=C(NCC=1C=CC=C(C1)N2CCN(C3=NC(=NC=C3OC)NC4=CC=CC(=C4)S(=O)(=O)N)CC2)C5=CC=C(C=C5)CCC(=O)NC

-20°C

Ice Packs

Small Compound