CDDD11-8 - CAS 2241659-94-7

CDDD11-8 is an orally administered, highly potent and selective CDK9 and FLT3-ITD inhibitor, with K i values of 8 nM and 13 nM, respectively. It effectively reduces the proliferation of leukemia cell lines, showing particular efficacy against those with the FLT3-ITD mutation [1] [2].

FLT, CDK

Tyrosine Kinase/Adaptors, Cell Cycle/Checkpoint, Angiogenesis

2241659-94-7

C24H26N6

398.5

CC=1C(C=2N3C(=NC2)C=CC(=C3)C4=CC=CC=C4)=NC(N[C@@H]5CC[C@@H](N)CC5)=NC1

-20°C

Ice Packs

Small Compound