CDK1-IN-1 - CAS 2761858-59-5

CDK1-IN-7 is a potent inhibitor of CDK1 with an IC50 value of 161.2 nM for CDK1/CycB. CDK1-IN-7 induces apoptosis in a p53-dependent manner via the apoptosis-intrinsic pathway. CDK1-IN-7 selectively acts on tumour tissue and has potential anti-proliferative effects. CDK1-IN-7 is a potential CDK1-IN-7 is a potential targeted anti-tumour agent.

Others, CDK

Cell Cycle/Checkpoint, Others

2761858-59-5

C27H23N5O3

465.5

C(N)(=O)C1=C2N(C(=CC(=N2)C3=CC=CC=C3)C4=CC=CC=C4)N=C1NC5=C(OC)C=C(OC)C=C5

-20°C

Ice Packs

Small Compound