CDK12/13 ligand 1 - CAS 2244986-40-9

ALK-IN-29 (compound 4c) exhibits notable inhibitory activity against tyrosine kinases such as ALK, CDK2/CyclinE1, and FAK, with the strongest inhibition observed against ALK kinase, showing a 40.63% inhibition rate at a concentration of 10 μM. ALK-IN-29 is useful for cancer research.

CDK

Cell Cycle/Checkpoint

2244937

C26H26BrN5O

504.42

N(C(NCC1=CC=CC=C1)=O)([C@H]2CC[C@H](NC3=CC=C(C#N)C=N3)CC2)C4=CC=C(Br)C=C4

-20°C

Ice Packs

Small Compound