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Molfinity

CDK12-IN-4 - CAS 2651196-69-7

CDK12-IN-4 - CAS 2651196-69-7

MF-0039986

$901.17 USD
$901.17 USD
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Product Details

  • Bioactivity

    CDK12-IN-4, a pyrazolotriazine compound, exhibits potent inhibition of CDK12 by achieving an IC50 value of 0.641 μM, utilizing high ATP levels (2 mM) . Notably, CDK12-IN-4 does not impact CDK2/Cyclin E (IC50 > 20 μM) or CDK9/Cyclin T1 (IC50 > 20 μM) under the influence of high ATP (2 mM) levels (WO2021116178A1) .

  • Target

    Others, CDK

  • Related Pathways

    Cell Cycle/Checkpoint, Others

  • CAS Number

    2651120

  • Molecular Formula

    C20H20F2N8O

  • Molecular Weight

    426.432

  • SMILES

    Fc1ccc2nc(CNc3nc(nc4c(cnn34)C3CC3)N3CCOCC3)[nH]c2c1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound